Mannitol Enhances Effectiveness of Dental Anesthesia

Mannitol Enhances Effectiveness of Dental Anesthesia

Mannitol can increase the success of local anesthetics in the inferior alveolar nerve block.

The most common local anesthetic injection is the inferior alveolar nerve block but it has a failure rate of anywhere from 10 to 39 percent.

This issue is analyzed in the current issue of the journal Anesthesia Progress.

To explain this research, 40 adults were part of a study and each received an IAN block on three occasions at least a week apart. The study looked at the ineffectiveness of a standard anesthetic, like lidocaine or epinephrine, and compared it to the ability of the combination of lidocaine with epinephrine and 0.5 M of mannitol. Mannitol is a sugar alcohol present in fruits and vegetables and can be excreted quickly by the kidneys.

Original Page: http://www.dentistrytoday.com/todays-dental-news/6665-mannitol-enhances-effectiveness-of-dental-anesthesia